杨玉姣
系 所:预防兽医系
职 称:讲 师
电子邮箱:yangyujiao@swu.edu.cn
讲授课程:本科课程:《兽医寄生虫病学》
研究生课程:《人兽共患病学》、《兽医寄生虫学与寄生虫病学》
个人简介
杨玉姣,女,成都蒲江人,讲师。从事人兽共患病毒病、蚊媒病毒病的防控与致病机制研究。先后主持及参与国家重点研发项目、国家自然科学基金面上项目和青年基金、重庆市院士牵头科技创新引导专项、重庆市社会事业与民生保障科技创新专项、中央高校基本科研业务费专项共8项科研项目,发表论文10余篇。
教育经历
2004.9–2008.7 吉林大学,生物技术,学士,理学学士
2008.9–2013.7 吉林大学,预防兽医学,博士,农学博士
工作经历
2020-至今欧洲杯买球正规平台,欧洲杯买球正规平台,讲师
2013/7 - 2020,欧洲杯买球正规平台,动物科技学院,讲师
2016/3-2017.9,美国德克萨斯大学医学分部(UTMB),访问学者
研究领域
主要从事重要人兽共患病毒病、蚊媒病毒病的防控与致病机制研究,研究领域涉及流行病学调查、快速检测与诊断技术研究、病毒-宿主互作机制研究。
科研项目
1、大熊猫与虎蚊传脑炎病毒病诊断与检测技术的研究,“十三五”国家重点研发计划项目子课题,2017YFD0501703,2017/7-2020/12,32万元,主持。
2、应用宏基因组学调查北碚区蚊媒中人兽共患病毒感染现状,中央高校基本科研业务费专项资金,XDJK2020C020,2020/01-2022/12,10万元,主持。
3、流行性乙型脑炎抗体胶体金快速检测试纸的研制,中央高校基本科研业务费专项资金项目一般项目,XDJK2014C121,2014/03-2016/12,5万元, 主持。
4、流行性乙型脑炎诊断抗原的研究,欧洲杯买球正规平台基本科研业务费专项资金项目博士启动项目,SWU113081,2014/01-2016/1,5万元,主持。
5、利用杆状病毒表达系统构建口蹄疫病毒样颗粒的研究,重庆市院士牵头科技创新引导专项,2018/10-2021/9,50万元,参加。
6、Calcineurin调节IgE介导肥大细胞脱颗粒的分子机制研究,国家自然科学基金面上项目,31770965,2018/01-2021/12,60万元,参加。
7、科学养殖助推高山农户脱贫致富,重庆市社会事业与民生保障科技创新专项一般项目,cstc2017shms-kjfp80052,2017/6-2019/12,20万元,参加。
8、表达鸡传染性支气管炎病毒S1和N蛋白重组新城疫病毒的构建及免疫保护评价,国家自然科学基金青年基金,31400784,2015/1-2017/12,25万元, 参加。
代表论文
1. Yujiao Yang, Chao Shan, Jing Zou, Antonio E. Muruato, Diniz Nunes Bruno, Barbosa de Almeida Medeiros Daniele,Pedro F.C. Vasconcelos, Shannan L. Rossi, Scott Weaver, Xuping Xie*, Pei-Yong Shi*. A cDNA clone-launched platform for high-yield production of inactivated Zika vaccine. EBioMedicine,2017,17: 145-156.
2. Yu-Jiao Yang, Ping-Sen Zhao, Hong-Xia Wu, Hua-Lei Wang, Li-Li Zhao, Xiang-Hong Xue, Wei-Wei Gai, Yu-Wei Gao, Song-Tao Yang, Xian-Zhu Xia*. Production and characterization of a fusion peptide derived from the rabies virus glycoprotein (RVG29)[J]. Protein expression and purification, 2014, 104: 7-13.
3. Yu-Jiao Yang, Ping-Sen Zhao, Tao Zhang, Hua-Lei Wang, Hong-Ru Liang, Li-Li Zhao, Hong-Xia Wu, Tie-Cheng Wang, Song-Tao Yang, Xian-Zhu Xia*. Small interfering RNAs targeting the rabies virus nucleoprotein gene. Virus Research, 2012, 169:169-174.
4. Pingsen Zhao, Yujiao Yang, Hao Feng, Lili Zhao, Junling Qin, Tao Zhang, Hualei Wang, Songtao Yang, Xian-Zhu Xia*. Global gene expression changes in BV2 microglial cell line during rabies virus infection. Infection, Genetics and Evolution, 2013, 20: 257-269.
5. Xuping Xie, Yujiao Yang, Antonio E. Muruato, Jing Zou, Chao Shan,Bruno T.D. Nunes, Daniele B.A. Medeiros, Pedro F.C. Vasconcelos, Scott C. Weaver, Shannan L. Rossi, Pei-Yong Shi*.Understanding Zika virus stability and developing a chimeric vaccine through Functional analysis.mBio, 2017,8(1): e02134-16.
6. Chao Shan, Daniel A. Ortiz, Yujiao Yang, Susan J. Wong, Laura D. Kramer, Pei-Yong Shi, Michael J. Loeffelholz, Ping Ren*. Evaluation of a Novel Reporter Virus Neutralization Test for Serological Diagnosis of Zika and Dengue Virus Infection. Journal of clinical microbiology. 2017,55(10):3028-3036.
7. Benjamin M. Akiyama, Hannah M. Laurence, Aaron R. Massey, David A. Costantino, Xuping Xie, Yujiao Yang, Pei-Yong Shi, Jay C. Nix, J. David Beckham, Jeffrey S. Kieft*. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science, 2016, 354(6316): 1148-1152.
8. Xuping Xie, JingZou, Chao Shan, Yujiao Yang, Dieudonné Buh Kum, Kai Dallmeier, Johan Neyts, Pei-Yong Shi*. Zika Virus Replicons for Drug Discovery. EBioMedicine, 2016, 12 :156–160.
9. Chao Shan, Xuping Xie, PingRen, Michael J. Loeffelholz, Yujiao Yang, Andrea Furuya, AlanP.DupuisII, Laura D. Kramer, Susan J.Wong, Pei-YongShi*. A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients. EBioMedicine, 2017, 17:157-162.
10. Chao Shan, Xuping Xie, Antonio E. Muruato, Shannan L. Rossi, Christopher M. Roundy, Sasha R. Azar, Yujiao Yang, Robert B. Tesh, Nigel Bourne, Alan D. Barrett, Nikos Vasilakis, Scott C. Weaver, and Pei-Yong Shi*. An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors. Cell Host & Microbe. 2016, 19(6): 891-900.
11. Hong-Xia WU, Hua-Lei WANG, Xiao-Feng GUO, Yu-Jiao YANG, Jin-Zhu MA, Tie-Cheng WANG, Yu-Wei GAO, Yong-Kun ZHAO, Song-Tao YANG, Xian-Zhu XIA*. Adeno-Associated Viruses Serotype 2-Mediated RNA Interference Efficiently Inhibits Rabies Virus Replication In Vitro and In Vivo. J. Vet. Med. Sci., 2013, 75(10): 1355–1361.
12. Hao Feng, Gui-qiu Hu, Hua-lei Wang, Meng Liang, Hongru Liang, He Guo, Pingsen Zhao, Yu-jiao Yang, Xue-xing Zheng, Zhi-fang Zhang, Yong-kun Zhao, Yu-wei Gao, Song-tao Yang, Xian-zhu Xia*. Canine parvovirus VP2 protein expressed in silkworm pupae self-assembles into virus-like particles with high immunogenicity[J]. PloS one, 2014, 9(1): e79575.
13. Hong-Ru Liang, Gui-Qiu Hu, Tao Zhang, Yu-Jiao Yang, Li-Li Zhao, Ying-lin Qi, Hua-Lei Wang, Yu-Wei Gao, Song-Tao Yang, Xian-Zhu Xia*. Isolation of ssDNA aptamers that inhibit rabies virus[J]. International immunopharmacology, 2012, 14(3): 341-347.
主要奖励
2015年获优秀班主任
2019年获优秀班主任
2019年获院教学比赛中级职称组“一等奖”